Modelling of transport-and-handling sites operation within metallurgical enterprises

In terms of existent regime of transport-and-handling sites operation, the necessity in enhancing the efficiency of production and transport interaction is justified. For this purpose simulation model of transport-and-handling site, which provides reception of raw materials, is developed

Gene expression as an indicator of long-term adaptation to physical activity

In order to achieve a high result in the course of sports training, the athlete’s body needs to constantly adapt to larger and larger training loads. Such trainings cause constant changes in the composition and properties of the biological system of the body. The relevance of the study is due to the need to use genetic testing both in sports selection and in sports training of athletes of different disciplines. The purpose of the study is to determine the genotypes that are associated with an increase in the performance and health of an athlete. During the analysis of scholarly researches on the subject some genetic markers affecting a person’s physical abilities were identified. The article also presents the results of scientific research reflecting the mechanisms of adaptation of the body to physical exertion

Annulation of Perimidines with 5-Alkynylpyrimidines en Route to 7-Formyl-1,3-Diazopyrenes

Unusual rearrangements were shown to accompany Brønsted acid-assisted peri-annulations of 1H-perimidines with 5-alkynylpyrimidines. These transformations take different routes depending on the nature of acetylene precursor, and lead to the formation of 7-formyl-1,3-diazopyrenes

Association of Myostatin Gene Polymorphisms with Strength and Muscle Mass in Athletes: A Systematic Review and Meta-Analysis of the MSTN rs1805086 Mutation

Polymorphism (rs1805086), c.458A>G, p.Lys(K)153Arg(R), (K153R) of the myostatin gene (MSTN) has been associated with a skeletal muscle phenotype (hypertrophic response in muscles due to strength training). However, there are not enough reliable data to demonstrate whether MSTN rs1805086 K and R allelic variants are valid genetic factors that can affect the strength phenotype of athletes’ skeletal muscles. The aim is to conduct a systematic review and meta-analysis of the association of MSTN rs1805086 polymorphism with the strength phenotype of athletes. This study analyzed 71 research articles on MSTN and performed a meta-analysis of MSTN K153R rs1805086 polymorphism in strength-oriented athletes and a control (non-athletes) group. It was found that athletes in the strength-oriented athlete group had a higher frequency of the R minor variant than that in the control group (OR = 2.02, P = 0.05). Thus, the obtained results convincingly demonstrate that there is an association between the studied polymorphism and strength phenotype of athletes; therefore, further studies on this association are scientifically warranted

Determining the speed of soil particles during the covering of set onion with a disk-type working element featuring a soil guide

In Russia, the major share of vegetable products is produced during the period of March to August. This is due to the inadequate volumes of vegetables fit for long-term storage, and the use of technologies of early production of vegetable cultures. Apart from the above, vegetable farming is highly dependent on imported seed stock. In view of the above, import phaseout and improvement of competitiveness of vegetable cultures in Russia should focus on the development of technologies of production of storable products, as well as on methods of early harvesting of vegetables (during the period of May to July). With regards to the production of bulb vegetables, this problem may be solved by expanding industrial cultivation of onions from set onions, as well as planting of both seeds and seedlings during the autumn season. In particular, techniques of production of set onion, bulb onion from seedlings, and of blackseed onion have poor scientific and methodological background. This deficiency results in a gap between domestic and international process and engineering aspects. This calls for the development and introduction of machines designed for production of onion from seedlings that would be in line with the modern level of development of farm machinery industry for vegetable production

Effects of Multi-Ingredient Pre-Workout Supplement and Caffeine on Bench Press Performance: A Single-Blind Cross-Over Study

The problem addressed in this study is the appropriateness of using different pre-training supplementation strategies and their ability to improve training performance and psychological measures. The aim of the study is the evaluation of the effectiveness of a multi-ingredient pre-workout supplement (MIPS) containing beta-alanine, L-citrulline malate, arginine alpha-ketoglutarate, L-taurine, L-tyrosine and caffeine compared to an exact dosage of anhydrous caffeine in bench press strength endurance, feeling scale (FS), felt arousal scale (FAS) and session rating of perceived exertion (sRPE). A group of fifteen resistance-trained males, weighing 83.92 ± 8.95 kg and having an average of 5.6 ± 3.38 years of training experience, tested their bench press 10 repetition maximum (79.01 ± 12.13). In a cross-over manner, they participated in two sessions where they were blinded to the order of supplementation they were given: either a MIPS including caffeine or caffeine alone. They completed the bench press strength endurance test with pre- and post-training psychological assessments containing FS, FAS and sRPE. Bench press repetition volume was greater after anhydrous caffeine than MIPS supplementation with no difference in psychological measures. These results indicate that MIPS supplementation is less ergogenic and cost effective than caffeine alone

DFT Modelling of Molecular Structure, Vibrational and UV-Vis Absorption Spectra of T-2 Toxin and 3-Deacetylcalonectrin

This paper discusses the applicability of optical and vibrational spectroscopies for the identification and characterization of the T-2 mycotoxin. Vibrational states and electronic structure of the T-2 toxin molecules are simulated using a density-functional quantum-mechanical approach. A numerical experiment aimed at comparing the predicted structural, vibrational and electronic properties of the T-2 toxin with analogous characteristics of the structurally similar 3-deacetylcalonectrin is performed, and the characteristic spectral features that can be used as fingerprints of the T-2 toxin are determined. It is shown that theoretical studies of the structure and spectroscopic features of trichothecene molecules facilitate the development of methods for the detection and characterization of the metabolites

Development of a methodological approach for the computational investigation of the coolant flow in the process of the sodium cooled reactor cooldown

A methodological approach has been developed for the computational investigation of the thermal-hydraulic processes taking place in a sodium cooled fast neutron reactor based on a Russian computational fluid dynamics code, FlowVision. The approach takes into account the integral layout of the reactor primary circuit equipment and the peculiarities of heat exchange in the liquid metal coolant, and makes it possible to model, using well-defined simplifications, the heat and mass exchange in the process of the coolant flowing through the reactor core, and the reactor heat-exchange equipment. Specifically, the methodological approach can be used for justification of safety during the reactor cooldown, as well as for other computational studies which require simulation of the integral reactor core and heat-exchange equipment. The paper presents a brief overview of the methodological approaches developed earlier to study the liquid metal cooled reactor cooldown processes. General principles of these approaches, as well as their advantages and drawbacks have been identified. A three-dimensional computational model of an advanced reactor has been developed, including one heat-exchange loop (a fourth part of the reactor). It has been demonstrated that the FlowVision gap model can be applied to model the space between the reactor core fuel assemblies (interwrapper space), and a porous skeleton model can be used to model the reactor’s heat-exchange equipment. It has been shown that the developed methodological approach is applicable to solving problems of the coolant flow in different operating modes of liquid metal cooled reactor facilities

On the volatility of nihonium (Nh, Z = 113

Gas-phase chromatography studies of nihonium (Nh, $Z=113$ were carried out at the one-atom-at-a-time level. For the production of nihonium, the heavy-ion-induced nuclear fusion reaction of$^{48}$ Ca with$^{243}$ Am was used. This leads to isotopes$^{284, 285}$ Nh, as the direct descendants of the $\alpha$ -decaying precursors$^{288, 289}$ Mc. Combining the Dubna Gas-Filled Recoil Separator with gas-phase chromatographic separation, the experiment was sensitive to elemental nihonium and its adsorption behavior on Teflon, theoretically predicted by modern relativistic density functional theory. The non-observation of any decays of Nh after the chemical separation indicates a larger than expected retention of elemental Nh on a Teflon surface